Sober living

Efforts to control alcohol addiction have just 50%–60% positive results in specific cessation programs 8,9. In fact, Brandt et al.54 observed that in ALDH2-deficient mice, the most important increase in mitochondrial superoxide levels (which is the major species of ROS) is due to acetaldehyde, not ethanol. By inhibiting NOX2 (the most important superoxide-producing alcoholic cardiomyopathy […]